Contraindicated (1)pentobarbital will lessen the extent or impact of roflumilast by impacting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will minimize the level or effect of dasatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital will reduce the extent or influence of estrogens c